Sphinx is an extensible document generator written in Python and uses reStructuredText as it's markup language. It creates intelligent and beautiful documentation, and has support for documenting several programming languages, different output formats, cross-references, Hierarchical structure, Automatic indices and Syntax Highlighting.

I gave a talk about it at PyWeb-IL 34 and (with some modifications) at Perl Mongers Tel-Aviv meeting at 03/2012.

The slides about Sphinx available at the Talks and presentations page.